Farfield’s proprietary innovation Dual Polarisation Interferometer, (DPI) is an analytical instrument for label free, real time measurement for molecular systems and interactions.
DPI is designed for the combined studies of affinity, kinetics, conformation and thermodynamics. Researchers are able to investigate and understand the intimate links between the structural changes in biomolecules their functions and interactions, to an extent not previously available in laboratory-based techniques. DPI is pioneering research breakthroughs in protein interactions, lipid biochemistry, diagnostic development, drug discovery, polymers, surfactants and glycobiology.
DPI routinely and reproducibly measures the structure of a protein in two dimensions - its size and density (i.e. mass per unit volume.) The technique resolves protein molecular structures down to subatomic dimensions (<0.1Å), providing a unique biochemical perspective into the structural changes taking place in molecular systems as they function and interact.
DPI provides the capability to understand the links between structural changes in biomolecules, their self assembly, folding/unfolding, denaturing event interactions and conformational changes to an extent not previously available in a laboratory-based technique.
Farfield's DPI technology for scientists, researchers and biophysics is advancing continually through customer collaboration. We are always looking forward to meeting the needs of the advance research activities of our customers.
- Two simultaneous measurements for- size, density and mass of captured biomolecules, mass and birefringence measurements
- Automated experimental scripts, data annotation and report generation
- Flexible temperature range from 5-65°, manual or scripted automatic control options. 50, 96, or 384 well formats - rapid transition times
Key benefits include:
- Conformational changes in biomolecules with picometer sensitivity
- Compare binding and conformational kinetics with unattended operation
- Run simultaneous experiments controls - with low sample volume requirements
Farfield Group Ltd
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